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Home › Research Catalog › MOTS-C

MOTS-C

Mitochondrial Peptide

MOTS-C

Mitochondrial-Derived Peptide16-mer PeptideLyophilized PowderCellular Signaling

MOTS-c is a 16-amino acid peptide encoded in the mitochondrial genome, studied in in-vitro cellular and mitochondrial research models. Available in 10mg and 40mg lyophilized vials.

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Description

What is MOTS-c?

MOTS-c is a 16-amino acid peptide encoded in the mitochondrial genome, studied in in-vitro cellular and mitochondrial research models. Available in 10mg and 40mg lyophilized vials. The 10mg lot GPU-4301315 was independently third-party tested to 99.39% purity (Horizon Analytical verified). For in-vitro laboratory research use only. Not for human consumption.

What Is MOTS-c?

MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA gene, one of a class of mitochondrial-derived peptides (MDPs). Each vial from Genetic Peptides USA is manufactured for in-vitro and laboratory research and is shipped from within the USA.

MOTS-c Research Context

MOTS-c is studied in metabolic and aging research for AMPK activation, glucose metabolism, and mitochondrial-nuclear signaling in cell and animal models. The information on this page summarizes published scientific context for educational purposes and is not a claim of any therapeutic effect.

Purity and Third-Party Testing

Every batch of MOTS-c is independently third-party tested using HPLC (high-performance liquid chromatography) for purity and mass spectrometry (MS) for identity confirmation. Where a Certificate of Analysis is available for the current lot, it is displayed on this page. Researchers should verify the lot number on the vial against the COA for their records.

Storage and Handling of Lyophilized MOTS-c

MOTS-c is supplied as a lyophilized (freeze-dried) powder, which is the most stable form for shipping and storage. Store unopened vials in a cool, dry place away from light; refrigeration at 2–8°C or freezing at -20°C is standard laboratory practice for long-term storage. Once reconstituted with a suitable solvent such as bacteriostatic water, keep refrigerated and follow your institution's handling protocols.

Why Researchers Choose Genetic Peptides USA

  • Third-party HPLC/MS tested batches
  • Lyophilized vials, sealed for stability
  • Fast USA shipping
  • Transparent lot documentation

MOTS-c FAQ for Researchers

Where can I buy MOTS-c in the USA? Genetic Peptides USA ships MOTS-c research peptide vials from within the United States with tracking on every order.

Is MOTS-c third-party tested? Yes. Batches are tested by an independent laboratory using HPLC/MS for purity and identity.

What form is MOTS-c supplied in? A lyophilized powder in a sealed vial, intended for reconstitution in a laboratory setting only.

Related Research Compounds

Research Use Only: MOTS-c is sold strictly for laboratory research use only. It is not for human or animal consumption, not a drug, food, or cosmetic, and is not intended to diagnose, treat, cure, or prevent any disease. Purchaser assumes responsibility for proper handling in accordance with applicable laws.

Related Research Guide: MOTS-c Research Peptide Overview

Research Applications

Areas of investigation in the preclinical literature

Mitochondrial
Mitochondrial-Derived Peptide Biology
Studied in the literature on mitochondrial-derived peptides (MDPs), a class of short peptides encoded within the mitochondrial genome. Investigated as a model compound for characterizing this signaling-peptide family in vitro.
Cellular
AMPK Pathway Signaling Research
Examined in preclinical and cell-based studies of AMP-activated protein kinase (AMPK) pathway activation. Used as a probe in research on cellular metabolic-stress signaling cascades.
Metabolic Pathways
Folate-Methionine Cycle Research
Investigated in in-vitro research on the folate-methionine one-carbon cycle and its tethered de novo purine biosynthesis pathway, including accumulation of the AICAR intermediate.
Gene Regulation
Nuclear Translocation Signaling
Studied in cell-based models of stress-responsive nuclear translocation and adaptive transcriptional regulation. A subject of research into how mitochondrial-encoded peptides participate in nuclear gene-expression signaling.
Skeletal Muscle
Metabolic Signaling in Muscle Tissue
Investigated in preclinical models of skeletal-muscle metabolic signaling and mitochondrial molecular pathways. Referenced in the literature as a tool compound for such mechanistic studies.

Compound Profile

Technical specifications

Identity
Molecular Profile
SequenceMRWQEMGYIFYPRKLR
Molecular FormulaC101H152N28O22S2
Molecular Weight2174.62 g/mol
CAS Number1627580-64-6
AppearanceWhite lyophilized powder
FormLyophilized (freeze-dried)
Handling guidelines
Storage & Stability
Storage
Store as a sealed lyophilized powder at room temperature, away from light and moisture. Room-temperature stable. Does not require refrigeration or cold-chain shipping.
Format
Supplied as a lyophilized (freeze-dried) powder, sealed under inert conditions.
Reconstitution
Reconstituted with bacteriostatic water (sold separately). Volume is determined by the researcher; no protocol or dosing is provided.
Compliance & research overview
Regulatory & Research Status
FDA Status
Not approved for human use. Sold for laboratory research use only.
Research Status
Studied in preclinical and in-vitro research literature.
Research Disclaimer
For laboratory and research purposes only. Not for human or animal consumption.

Certificate of Analysis

Third-party tested by Horizon Analytical (USA)

99.39%
Purity
CompoundMOTS-C
Lot #GPU-4301315
MethodHPLC / MS
LabHorizon Analytical
📄 View COA

Reconstitution

🧪 Reconstitution CalculatorYou set the values

Pure dilution math, concentration = peptide mass ÷ water volume. You determine your own volumes for your protocol. Bacteriostatic water sold separately. For in-vitro laboratory research use only.

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Common Questions

What is this product used for? ▼
This compound is supplied strictly for in-vitro laboratory research and scientific study by qualified researchers. It is not for human or veterinary use, consumption, or cosmetic application.
Who tests it and how do I verify purity? ▼
Where we hold a lot-matched Certificate of Analysis, it is produced by Horizon Analytical (USA), HPLC purity analysis and mass-spectrometry identity confirmation. The lot-matched Certificate of Analysis is published in our COA Library, and our results are cross-checked live by the independent watchdog PepAssure.
How is it stored and shipped? ▼
The compound ships as a stable lyophilized powder that is room-temperature stable and does not require refrigerated shipping. Orders are dispatched within roughly 48 hours by UPS Ground in plain, unmarked packaging. We ship within the United States only.
What is used to reconstitute it? ▼
Lyophilized research compounds are reconstituted with bacteriostatic water, which is sold separately. The reconstitution volume is determined by the researcher; we do not provide any protocol or dosing guidance.
Do you offer discounts for larger orders? ▼
Yes. Order 2 vials of the same compound for 3.5% off, or 3 or more for 5% off. The discount is counted per compound, applies automatically at checkout, and stacks with a discount code. Orders over $150 ship free, and orders over $200 ship free by UPS 2nd Day Air.

Disclaimer: This product is intended solely for in-vitro scientific research by qualified researchers. It is not a drug, food, or cosmetic. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. Statements not evaluated by the FDA. By purchasing you confirm you are a qualified researcher and assume full legal responsibility for compliance. Certificate of Analysis provided by Horizon Analytical (USA), lot number on COA corresponds to shipped batch. View All COAs.

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